NAD+ is the cellular fuel your body uses to repair DNA, regulate metabolism, and resist oxidative stress. After 40, levels can drop ~50%.
PeakRx's NAD+ Precursor Complex pairs nicotinamide mononucleotide (NMN) with nicotinamide riboside (NR) — the two best-studied direct precursors — at the dose ranges used in human clinical trials. Once daily, with or without food.
What to expect
- NMN + NR dual precursor
- Clinical-trial dosing
- NABP-accredited pharmacy
How it works
How it works
NAD+ can't be absorbed orally — the molecule is too unstable to survive digestion. Your body builds NAD+ from precursor molecules instead.
- NMN is one step away from NAD+ in the salvage pathway. It's converted by the enzyme NMNAT to NAD+ inside the cell.
- NR enters the pathway one step earlier, via the NRK1/NRK2 enzymes, and is converted first to NMN, then to NAD+.
Pairing both precursors gives your salvage pathway redundancy — if one route is bottlenecked (genetic variation in NMNAT or NRK1 is common), the other compensates. Trials with NR alone have shown 40-60% increases in blood NAD+ over 4-8 weeks at 250-500mg/day. Combining NMN brings additional upstream substrate.
Why this formula
Why this formula
Most NAD+ supplements give you one precursor or a microdose of several. Ours is built on three principles:
- Both NMN and NR in one capsule — covers both salvage routes
- Clinical-trial dosing — 500mg total active precursors, not the 50-100mg you'll find at health food stores
- Made in a NABP-accredited compounding pharmacy in the United States, with third-party purity testing on every lot
We don't add stimulants, "proprietary blends," or fillers that obscure dose.
What happens next
- 1Complete your intake
Answer a few questions about your health history and treatment goals.
- 2Provider review
A licensed provider will review your information and create a personalized plan.
- 3Receive your treatment
Your prescription is sent to the pharmacy and shipped directly to you.
Frequently asked questions
Is NMN still legal as a supplement?
Yes. As of 2026 NMN is sold as a dietary supplement in the US. The FDA reviewed NMN under NDIN status in 2022 and has not removed it from the supplement market. PeakRx will pause sales immediately if regulatory posture changes.
When will I notice anything?
Most patients report subjective changes in energy and sleep quality between weeks 3 and 6. Blood NAD+ measurements typically rise within the first 4 weeks. NAD+ is not a stimulant — there is no acute "feeling" within hours of taking it.
Can I take this with other supplements or medications?
NAD+ precursors are generally well tolerated alongside common supplements (vitamin D, magnesium, omega-3) and most prescription medications. If you take chemotherapy, immunosuppressants, or are pregnant or breastfeeding, do not start without your physician's approval.
How is this different from buying NMN on Amazon?
Three things. (1) Dose — ours is 500mg total active precursors, most Amazon products are 125-250mg. (2) Pharmacy quality — we manufacture in a NABP-accredited compounding pharmacy with COA on every lot. (3) Clinician oversight — your intake is reviewed by a licensed physician before dispensing.
Do I need to cycle off?
No evidence currently supports cycling. The body downregulates absorption modestly over time but does not appear to develop tolerance. We re-evaluate every 6 months as new long-term safety data publishes.
Treatment overview
- Category
- General Care
- Type
- Supplement
- Available doses
- 500mg
- Provider review
- Online review (no appointment needed)
- Fulfilled by
- PeakRx Compound Pharmacy
Ready to get started?
Complete your intake in just a few minutes. A licensed provider will review your information.
Start intake for NAD+ Precursor Complex